<em>Improving the Performance of Narrow-bore HPLC Columns Using Active Flow Technology</em> — ASN Events
  1. Schedule
  2. Poster Session 1
  3. Improving the Performance of Narrow-bore HPLC Columns Using Active Flow Technology

Improving the Performance of Narrow-bore HPLC Columns Using Active Flow Technology (#195)

Arianne Soliven , Dominic Foley 1 , Luisa Pereira 1 , Tony Edge 1 , Harrald Ritchie 1 , Gary R Dennis 2 , R Andrew Shalliker 2
  1. Thermo Fisher Scientific, Manor Park, Tudor Road, Runcorn, UK
  2. Australian Centre for Research on Separation Science (ACROSS), School of Science and Health, University of Western Sydney, Parramatta, NSW, Australia

Active flow technology (AFT) columns are designed to remove inefficient flow processes associated with the column wall and radial heterogeneity. This study is the first to explore AFT on a 2.1 mm internal diameter (I.D) column, emulating a 1.0 mm I.D column. The performance of the AFT column was compared to a conventional 1.0 mm I.D column; at the highest linear velocities tested it was observed that the AFT column functioning as a virtual 1.0 mm I.D column had an efficiency gain that was 58% compared to the conventional 1 mm I.D column.