The Raptor Biphenyl Stationary Phase: Selectivity Accelerated — ASN Events

The Raptor Biphenyl Stationary Phase: Selectivity Accelerated (#130)

Ty Kahler 1 , Paul Connolly 1 , Sharon Lupo 1 , Shun-Hsin Liang 1 , Frances Carroll 1
  1. Restek Corporation, Bellefonte, PA, United States

With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (SPP) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.
Our top priority when developing our new SPP line was to create a version of our innovative Biphenyl. The Biphenyl ligand provides greater aromatic selectivity than commercially available
phenyl-hexyl columns and a greater degree of dispersion than conventional phenyls. This unique selectivity mechanism allows greater retention of dipolar compounds, conjugated compounds, and compounds containing strong electron withdrawing groups. The industry-leading Biphenyl is Restek’s most popular LC stationary phase because it is particularly adept at separating compounds that are hard to resolve or that elute early on C18 and other phenyl chemistries. Increasing retention of early-eluting can limit ionization suppression, and the heightened selectivity helps eliminate the need for com¬plex mobile phases that are not well-suited for MS detection.